So, when should you take a dose of creatine? The short answer is both pre and post workout. Before training it would be wise to load your muscle cells with this super supplement to reap the advantages early on. But let's not forget about the critical post-workout recovery opportunity.. Yes, it's fine to mix creatine with pre-workout. It is not dangerous to mix creatine with pre-workout and the only potential negative side effect may be some stomach discomfort. In fact, many pre-workouts already contain creatine. If you're concerned about how you may react to mixing creatine with pre-workout, it's fine to take creatine.

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Creatine and Pre-Workout: Benefits. Combining creatine with a pre-workout supplement can offer synergistic benefits. Since the benefits of creatine include enhanced strength, muscle mass, and power, adding a pre-workout to the mix can give you the energy and focus boost needed to get the most out of your training.. Camp 1: Before a Workout. The argument for taking creatine before a workout is usually based on this thought process: More creatine equals more ATP, the primary currency of cellular energy. More ATP means more power available to the muscles. More power means more activation of muscle fibers and more weight lifted. More weight means more muscle.